July 11, 1991 – Nigeria Airways Flight 2120, a Nationair McDonnell Douglas DC-8 chartered by Nigeria Airways to transport Nigerian pilgrims to Mecca, crashes shortly after takeoff from King Abdulaziz International Airport, Jeddah, Saudi Arabia, due to a fire caused by tire failure. All 261 on board die, including 14 Canadian crew members.
December 22, 1992 – Libyan Arab Airlines Flight 1103, a Boeing 727, collides with a Libyan Air Force MiG-23 near Tripoli International Airport, killing all 159 on board both aircraft.
January 8, 1996 – Air Africa crash, an overloaded Antonov An-32 aborts takeoff and overruns into a market in Kinshasa, Democratic Republic of the Congo, killing 227 people on the ground.
November 7, 1996 – ADC Airlines Flight 86, a Boeing 727, crashes when the crew loses control of the aircraft while avoiding a mid-air collision on approach to Lagos, Nigeria. All 144 passengers and crew on board are killed.
November 23, 1996 – Ethiopian Airlines Flight 961, a Boeing 767, is hijacked over Kenya. The aircraft runs out of fuel, and the pilot attempts to ditch the aircraft in the ocean off Moroni, Comoros. Of the 175 people on board, 125 are killed (including the three hijackers).
January 30, 2000 – Kenya Airways Flight 431, an Airbus A310, carrying 169 passengers and 10 crew members, crashes into the Atlantic Ocean off Côte d’Ivoire after takeoff from Abidjan. Only 10 people survive.
May 4, 2002 – EAS Airlines Flight 4226, a BAC 1–11 500 series, crashes into the Gwammaja neighborhood at Kano, Nigeria, shortly after takeoff; the ensuing crash resulted in the deaths of 71 passengers and at least 78 civilians on the ground.
July 8, 2003 – Sudan Airways Flight 139, a Boeing 737-200, crashes shortly after taking off from Port Sudan, Sudan. All 117 people on board the plane perish; a two-year-old boy initially survives the crash, but dies the following day.
December 25, 2003 – UTAGE Flight 141, a Boeing 727, runs off the end of the runway upon takeoff at Cotonou, Benin, and crashes onto the beach on the Bight of Benin, killing 151 of the 163 occupants.
October 22, 2005 – Bellview Airlines Flight 210, a Boeing 737-200, crashes shortly after takeoff from Murtala Muhammed International Airport in Lagos, Nigeria, killing all 117 people on board.
December 10, 2005 – Sosoliso Airlines Flight 1145, a McDonnell Douglas DC-9 with 110 people on board, crashes during landing in Port Harcourt, Nigeria. Of the 110 people on board; only two survive.
October 29, 2005 – ADC Airlines Flight 53, a Boeing 737-200, crashes near Abuja, Nigeria, after encountering wind shear, killing 96 of the 105 people on board.
May 5, 2007 – Kenya Airways Flight 507, a Boeing 737-800 with 114 people on board, crashes near Douala, Cameroon, killing all on board.
June 3, 2012 – Dana Air Flight 992, a McDonnell Douglas MD-83 carrying 147 passengers and six crew members crashes in a suburb of Lagos, Nigeria, on approach to Murtala Muhammed International Airport, killing all on board and 10 more people on the ground.
July 24, 2014 – Air Algérie Flight 5017, a chartered Swiftair McDonnell Douglas MD-83 operating for Air Algérie en route from Burkina Faso to Algiers, crashes in the northern Mali desert after disappearing from radar approximately 50 minutes after takeoff, killing all 110 passengers and six crew members on board.
March 10, 2019 – Ethiopian Airlines Flight 302, a Boeing 737 MAX 8, crashes near Bishoftu, Ethiopia six minutes after taking off from Bole International Airport. All 157 passengers and crew are killed.