Juventus captain Giorgio Chiellini and midfielder Emre Can are unavailable for the first leg match of the UEFA Champions League quarter-final fixture at Ajax, the Italian champions said on Tuesday.
Central defender Chiellini is out with a pulled left calf for Wednesday’s match in Amsterdam.
Also, German midfielder Can sprained his right ankle during a weekend league clash with AC Milan.
However, the return of Portugal star Cristiano Ronaldo to the squad was confirmed.
He had been out since pulling a thigh muscle playing a Euro 2020 qualifier on March 25.